cystic fibrosis

MECFA Blog

Disease Duration, Flare-ups Affect Mental Health of Non-CF Bronchiectasis Patients, Study Finds

People with non-cystic fibrosis (CF) bronchiectasis are at an increased risk for anxiety and depression, and this risk is associated with...

VERTEX’S CF BLOCKBUSTER TRIKAFTA EFFECTIVE IN KIDS 6 TO 11 YEARS OF AGE

Vertex Pharmaceuticals announced the completion of its Phase III trial of Trikafta in children ages 6 through 11 years with cystic...

A case for improved carrier screening

Expanded carrier screening addresses limitations in historical ethnic-based screenings, including potential racial and ethnic bias....

Vertex to Seek Expanded FDA Approval for Trikafta After Positive Child Safety Data

Trikafta (elexacaftor/tezacaftor/ivacaftor and ivacaftor) is safe for use in children with cystic fibrosis (CF) as young as age 6, data...

Age May Affect Outcomes in Lung Transplant Recipients With Cystic Fibrosis

Age may influence outcomes in lung transplant recipients with cystic fibrosis (CF), according to study results published in the Annals of...

CFF Funding Will Further ContraFect’s Research Into Alternative for Antibiotics

ContraFect will receive funding from the Cystic Fibrosis Foundation to conduct preclinical research about the potential of direct lytic...

The search for molecular glue in targeted disease control

In cells, there are proteins that do the work and proteins that regulate them. The latter inhibit or enhance activity, depending on the...

Vest Therapy Lowers Risk of Hospitalization in Non-CF Bronchiectasis, Study Says

One year of vest therapy with high frequency chest wall oscillation (HFCWO) can reduce the risk of hospitalization and the use of...

Harvard is working with Boston hospitals to test existing cystic fibrosis drug to help coronavirus p

Researchers at Harvard University announced this week it will begin examining if an existing drug used to treat cystic fibrosis could...

Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis L

Neutrophil elastase (NE) is a major protease in the airways of patients with cystic fibrosis (CF) that activates airway inflammation by...