What doctors wish patients knew about cystic fibrosis
Cystic fibrosis treatments are improving patients’ quality of life. Three physicians from University of Iowa Health Care share more about cystic fibrosis. By Sara Berg, MS News Editor Cystic fibrosis (CF) is a lifelong genetic condition that primarily affects the lungs and digestive system, making everyday tasks like breathing and eating more difficult than most people ever realize or experience. Caused by changes in a single gene, cystic fibrosis leads to thick, sticky mucu


How my life after lung transplant differs from my life with CF
I'm still learning to navigate a new set of health challenges Written by Jennifer Cogliano Five and a half years ago, I received the gift of a lifetime: a double-lung transplant that gave me back my breath and, in many ways, my life. After decades of fighting cystic fibrosis (CF), I finally felt free. And then reality set in. Nobody tells you that a transplant isn’t a finish line. It’s more like a beautiful, necessary, lifesaving detour that leads you onto a completely diffe


Gene Therapy Breakthrough Restores Key Function in Cystic Fibrosis
RESEARCHERS at University California, Los Angeles (UCLA) have developed a lipid nanoparticle (LNP)-based system capable of delivering the full cystic fibrosis transmembrane conductance regulator (CFTR) gene into human airway cells. The LNPs carry CRISPR/Cas9 components, guide RNAs, and a linear DNA template for homology-directed repair, allowing precise insertion of the complete CFTR gene without the use of viral vectors. This non-viral approach overcomes limitations associat


It’s time to stop obsessing over life expectancy in CF
I’ve never met anyone who found this information helpful Written by Lara Govendo “You might live long enough to finish college, maybe even get married, but …” I imagine this is what the textbooks used to say about cystic fibrosis (CF) when I was in college. While I heard such things at medical appointments, I refused to let that narrative define my life. Yet many medical professionals seem to consider this a necessary conversation with patients. Not with this patient , thoug


Handgrip test reflects breathing muscle strength in adults with cystic fibrosis
Study suggests a simple measure could complement lung function testing Written by Steve Bryson , PhD Handgrip strength was associated with breathing muscle strength in adults with cystic fibrosis (CF), according to a new study, suggesting the simple test may help complement standard lung function tests in clinical care. The research also found that lung function and breathing muscle strength were related to a combination of factors, including handgrip strength, physical ac


MECFA Launches “MADI: The Path to Progress” A Regional Initiative to Build Diagnostic Pathways for Children with Cystic Fibrosis
Izmir February 13, 2026 — The Middle East Cystic Fibrosis Association (MECFA) has officially launched MADI: The Path to Progress, a three-year regional initiative designed to address one of the most critical barriers facing children with cystic fibrosis (CF) across the Middle East, North Africa, and parts of Central and South Asia: lack of diagnosis. While scientific breakthroughs have transformed cystic fibrosis care in high-income countries, many children in low- and middle


























