AzurRx BioPharma's OPTION 2 Trial Of MS1819 In Cystic Fibrosis Fails, What Next?
(RTTNews) - AzurRx BioPharma Inc.'s (AZRX) phase IIb study of MS1819 for the treatment of exocrine pancreatic insufficiency in patients...
“Sweat Stickers” May Ease Cystic Fibrosis Diagnosis and Management
An elevated chloride concentration in an infant’s sweat is indicative of the genetic, progressive disease cystic fibrosis. Many current...
CHMP Favors Kaftrio to Treat CF Patients in EU Starting at Age 12
A European Medicines Agency (EMA) committee favors extending the label for Kaftrio (ivacaftor/tezacaftor/elexacaftor), in combination...
Elexacaftor-Tezacaftor-Ivacaftor Associated With Rapid Improvement in Cystic Fibrosis
In patients with cystic fibrosis (CF) with advanced lung disease, initiation of elexacaftor-tezacaftor-ivacaftor is associated with rapid...
Computer-designed Enzyme May Help to Kill P. aeruginosa in Biofilms
An enzyme produced using computer design, in combination with the antibiotic tobramycin, efficiently kills Pseudomonas aeruginosa, a...
Translate Bio Continues Trial of Inhaled Cystic Fibrosis mRNA Despite Setback
Translate Bio says it is continuing its Phase I/II trial of its inhaled mRNA cystic fibrosis (CF) candidate MRT5005 despite it showing a...
Translate Bio’s MRT5005 Shows Safety and Tolerability at Multiple Doses in Trial
Translate Bio’s ongoing Phase 1/2 clinical trial investigating MRT5005, its candidate inhalation therapy for cystic fibrosis (CF), found...
Analysis of GI Tract Finds High CFTR Gene Activity in Small Intestine
Molecular analysis of single cells lining the digestive tract found high CFTR activity — the gene associated with cystic fibrosis (CF) —...
Living with an invisible illness
I often describe the disease I’m living with as an invisible illness. If you walk by me in the grocery store, or see me dropping my...
Microorganisms utilize vile methodology to vanquish antibody that battle cystic fibrosis
University of Montana researchers and their partners have found a slimy strategy used by bacteria to conquer antibiotics and other...
