Lung damage bacteria sniffed out by dogs in cystic fibrosis research
A new study found the animals can detect ultra-low concentrations of pseudomonas, the commonest cause of lung infection in the disease....
Minimally Invasive Imaging Device Shows Changes in Nasal Airways, May Allow Earlier CF Diagnosis
A minimally invasive imaging device that generates high-resolution images of nasal airways, including the cilia and mucus, allows...
Proteostasis Begins Dosing in Phase 2 Trial of 3 CF Investigational Therapies
The first patient has been dosed in a Phase 2 clinical trial testing Proteostasis Therapeutics‘s combinations of three investigational...
Pregnancy in CF Women With Poor Lung Function Not Linked to Pulmonary Decline, Study Shows
Poorer lung function in pregnant women with cystic fibrosis (CF) is associated with a lower birth weight for offspring, and a higher...
Tezacaftor, Ivacaftor Combination Generally Safe, Well Tolerated in Children With CF Under Age 12
Data from a phase 3 trial are supporting the use of tezacaftor in combination with ivacaftor for the treatment of cystic fibrosis (CF) in...
Different CFTR Potentiators Bind to Same Flexible Spot on Protein, Study Finds
Approved and investigative cystic fibrosis (CF) treatments known as CFTR potentiators work by binding to the same flexible protein spot —...
Eluforsen Improves CFTR Function in Cellular and Animal Models of CF, Study Says
Eluforsen, an investigational therapy for the treatment of cystic fibrosis (CF), improves the function of the cystic fibrosis...
Kalydeco’s Safety and Benefits Studied in CF Patients with Severe Lung Disease
Treatment with Kalydeco (ivacaftor) improved lung function, exercise capacity, and sweat chloride concentration in cystic fibrosis (CF)...
Specific Variables Improve Disease Severity Discrimination Among CF Transplant Candidates
The inclusion of Cystic Fibrosis Foundation Patient Registry variables in the lung allocation score (LAS) calculation allowed for...
Babies Treated with Synagis Show No Lasting Benefits in Lung Health as 7-Year-Olds, Real-world Study
Treating infants with cystic fibrosis (CF) with the antiviral therapy Synagis(palivizumab) does not improve long-term outcomes in lung...
