Developing a first-in-class regenerative gene therapy for cystic fibrosis
OmniSpirant Limited is an Irish company developing a regenerative gene therapy with the potential to transform respiratory medicine. The...
Lung Enzyme Cathepsin S is New Therapeutic Target for CF and COPD
Blocking the enzyme cathepsin S can alleviate symptoms and reduce lung damage in cystic fibrosis (CF) and chronic obstructive pulmonary...
Non-invasive Ventilation Improves Lung Function in CF Patients But Not Survival, Study Finds
A reassessment of U.K. medical records showed that in cystic fibrosis (CF) patients, breathing support provided by gas inhalation,...
Triple Combo Treatment Improves Lung Function in Patients with Cystic Fibrosis
An investigational triple combination treatment regimen for cystic fibrosis (CF) improved patients’ lung function in 2 phase 3 studies,...
Mucus Protects Lungs by Forming Layers, Preventing Worsening of Lung Diseases, Studies Reveal
Two new studies highlight the important role of mucus in cleaning and protecting the lungs, and how its accumulation and impaired...
New cystic fibrosis drugs significantly improve lung function
A triple drug combination for treating the underlying cause of cystic fibrosis is currently under study. The preliminary results show a...
Law Student returned to life with lung transplantation
Law student came back to life with lung transplantation, 20 years of law student struggles with genetic disease ISTANBUL – For many...
PTI-808 and PTI-801 Combo Improves Lung Function in CF Patients, Phase 1 Data Show
Treatment with a combo of Proteostasis Therapeutics’ investigational CFTR modulator therapies — PTI-808, a potentiator, plus PTI-801, a...
Gene Mutations Linked to Other Lung Diseases May Contribute to Bronchiectasis, Study Suggests
Mutations in genes linked to other lung diseases, specifically cystic fibrosis and primary ciliary dyskinesia, may also contribute to...
New Method to Deliver Bacteria-killing Viruses Seen to Resolve Lung Infections in CF Mice
A new therapy which is administered directly into the lung of viruses can kill bacteria, and was shown to be effective in reducing...
